POLY ETHYLENE GLYCOL (PEG)- 6000
Physical & Chemical Properties Of PEG-6000:
- Boiling Pt: Min. 250°C (1013 hPa)
- Melting Pt: 55 to 62 °C
- Density: 1.13 g/cm³ (20°C)
- Appearance White or almost white, waxy or paraffin-like
- Solubility: Soluble in water
Description
Polyethylene glycol, referred to as PEG, is used as an inactive ingredient in the pharmaceutical industry as a solvent, plasticizer, surfactant, ointments and suppository base, and tablet and capsule lubricant. PEG has low toxicity with systemic absorption less than 0.5%.
- PEG is the basis of a number of laxatives. Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy.
- PEG is also used as an excipient in many pharmaceutical products.
- When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood.
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